Abeomics/Recombinant Rabbit Monoclonal Antibody to Chromogranin A / CHGA (Neuroendocrine Marker)(Clone : CHGA/1773R)/20 µg/12-1017-免疫在线蚂蚁淘旗下平台

商品详细Abeomics/Recombinant Rabbit Monoclonal Antibody to Chromogranin A / CHGA (Neuroendocrine Marker)(Clone : CHGA/1773R)/20 µg/12-1017

Abeomics/Recombinant Rabbit Monoclonal Antibody to Chromogranin A / CHGA (Neuroendocrine Marker)(Clone : CHGA/1773R)/20 µg/12-1017

商品编号： 12-1017

品牌： Abeomics

市场价： ¥3980.00

美元价： 1990.00

产地：美国(厂家直采)

公司：

产品分类： DNA文库制备试剂盒

公司分类： DNA_library_preparation

联系Q Q： 3392242852

电话号码： 4000-520-616

电子邮箱： info@ebiomall.com

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商品介绍

Format :	Purified
Amount :	100 µg
Isotype :	Rabbit IgG, kappa
Purification :	Purified Ab with BSA and Azide at 200ug/ml
Content :	200ug/ml of Ab purified by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Storage condition :	Store the antibody at 4°C; stable for 6 months. For long-term storage; store at -20°C. Avoid repeated freeze and thaw cycles.


Gene :	CHGA
Gene ID :	1113
Uniprot ID :	P10645
Alternative Name :	Beta-Granin,CGA,CHGA,Chromogranin A Parathyroid Secretory Protein 1,ER-37,Pancreastatin,Parastatin,Parathyroid Secretory Protein 1,Pituitary Secretory Protein I,SP-I,Vasostatin I or II
Immunogen Information :	Recombinant human full-length Chromogranin A protein

Chromogranin A is present in neuroendocrine cells throughout the body, including the neuroendocrine cells of the large and small intestine, adrenal medulla and pancreatic islets. It is an excellent marker for carcinoid tumors, pheochromocytomas, paragangliomas, and other neuroendocrine tumors.Co-expression of chromogranin A and neuron specific enolase (NSE) is common in neuroendocrine neoplasms. Reportedly, co-expression of certain keratins and chromogranin indicates neuroendocrine lineage. The presence of strong anti-chromogranin staining and absence of anti-keratin staining should raise the possibility of paraganglioma. The co-expression of chromogranin and NSE is typical of neuroendocrine neoplasms. Most pituitary adenomas and prolactinomas readily express chromogranin.

Does not react with rat.

MW : 68-75kDa; Positive Control : PC12 cells. Adrenal gland, bowel, parathyroid, pancreas, or pheochromocytoma.;Flow Cytometry (0.5-1ug/million cells); Immunofluorescence (1-2ug/ml); Immunohistology (Formalin-fixed) (0.25-0.5ug/ml for 30 minutes at RT),(Staining of formalin-fixed tissues requires boiling tissue sections in 10mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes) ,Optimal dilution for a specific application should be determined.

For Research Use Only. Not for use in diagnostic/therapeutics procedures.

Subcellular location:	Secreted, Cytoplasmic vesicle
Post transnational modification:	Proteolytic processing gives rise to an additional longer form of catestatin (residues 358-390) which displays a less potent catecholamine release-inhibitory activity (PubMed:10781584). Plasmin-mediated proteolytic processing can give rise to additional shorter and longer forms of catestatin peptides (PubMed:17991725).
Tissue Specificity:	GE-25 is found in the brain.
BioGrid:	107538.12 interactions.

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