抗结蛋白单克隆抗体（克隆：BS21）/0.1 ml/10-12520-免疫在线蚂蚁淘旗下平台

商品详细抗结蛋白单克隆抗体（克隆：BS21）/0.1 ml/10-12520

抗结蛋白单克隆抗体（克隆：BS21）/0.1 ml/10-12520

商品编号： 10-12520

品牌： Abeomics

市场价： ¥9120.00

美元价： 4560.00

产地：美国(厂家直采)

公司：

产品分类：杂交仪

公司分类： Hybridization_apparatus

联系Q Q： 3392242852

电话号码： 4000-520-616

电子邮箱： info@ebiomall.com

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商品介绍

Format :	concentrate
Amount :	0.5 ml
Isotype :	Mouse IgG1
Content :	TRIS with 0.03% sodium azide, pH7.2
Storage condition :	Store at 4°C


Gene :	DES
Gene ID :	1674
Uniprot ID :	P17661
Alternative Name :	Desmin, DES

Desmin (DES), with 470-amino acid protein (about 52kDa), belongs to the intermediate filament family and Desmin is class III intermediate filaments found in muscle cells. Homopolymers of Desmin form a stable intracytoplasmic filamentous network connecting myofibrils to each other and to the plasma membrane.Mutations in Desmin are associated with desmin-related myopathy, a familial cardiac and skeletal myopathy (CSM), and with distal myopathies.Desmin is also expressed in smooth muscle cells of both airways and alveolar ducts and Desmin is a load-bearing protein that stiffens the airways and consequently the lung and modulates airway contractile response.

Immunohistochemical Analysis :-1:200

For Research Use Only. Not for use in diagnostic/therapeutics procedures.

Subcellular location:	Cytoplasm, Cytoplasm, Cell membrane, Nucleus
Post transnational modification:	Phosphorylation at Ser-7, Ser-28 and Ser-32 by CDK1, phosphorylation at Ser-60 by AURKB and phosphorylation at Thr-76 by ROCK1 contribute to efficient separation of desmin intermediate filaments during mitosis.
Tissue Specificity:	Cardiac progenitor cells and immature cardiomyocytes (at protein level).
BioGrid:	108038.47 interactions.

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