Abeomics/抗雄激素受体的小鼠单克隆抗体（克隆：BS46）/0.1 ml/10-12534-免疫在线蚂蚁淘旗下平台

商品详细Abeomics/抗雄激素受体的小鼠单克隆抗体（克隆：BS46）/0.1 ml/10-12534

Abeomics/抗雄激素受体的小鼠单克隆抗体（克隆：BS46）/0.1 ml/10-12534

商品编号： 10-12534

品牌： Abeomics

市场价： ¥9120.00

美元价： 4560.00

产地：美国(厂家直采)

公司：

产品分类：电生理设备

公司分类： Electrophysiological

联系Q Q： 3392242852

电话号码： 4000-520-616

电子邮箱： info@ebiomall.com

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商品介绍

Amount :	0.5 ml
Isotype :	Mouse IgG1
Content :	TRIS with 0.03% sodium azide, pH7.2
Storage condition :	Store at 4°C


Gene :	AR
Gene ID :	367
Uniprot ID :	P10275
Alternative Name :	Dihydrotestosterone receptor, Nuclear receptor subfamily 3 group C member 4, DHTR, NR3C4

The androgen receptor (AR), also known as NR3C4 (nuclear receptor subfamily 3, group C, member 4), is a type of nuclear receptor which is activated by binding of either of the androgenic hormones testosterone or dihydrotestosterone in the cytoplasm and then translocating into the nucleus. The androgen receptor is most closely related to the progesterone receptor, and progestins in higher dosages can block the androgen receptor. The main function of the androgen receptor is as a DNA binding transcription factor which regulates gene expression; however, the androgen receptor has other functions as well. Androgen regulated genes are critical for the development and maintenance of the male sexual phenotype.

Immunohistochemical Analysis :-1:200

For Research Use Only. Not for use in diagnostic/therapeutics procedures.

Subcellular location:	Nucleus, Cytoplasm
Post transnational modification:	Palmitoylated by ZDHHC7 and ZDHHC21. Palmitoylation is required for plasma membrane targeting and for rapid intracellular signaling via ERK and AKT kinases and cAMP generation.
Tissue Specificity:	Isoform 2 is mainly expressed in heart and skeletal muscle (PubMed:15634333). Isoform 3 is expressed by basal and stromal cells of prostate (at protein level) (PubMed:19244107).
BioGrid:	106862.284 interactions.

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