Abomics/抗AKT1单克隆抗体（克隆：ABM12F7）/25µg/10-1010-免疫在线蚂蚁淘旗下平台

商品详细Abomics/抗AKT1单克隆抗体（克隆：ABM12F7）/25µg/10-1010

Abomics/抗AKT1单克隆抗体（克隆：ABM12F7）/25µg/10-1010

商品编号： 10-1010

品牌： Abeomics

市场价： ¥1800.00

美元价： 900.00

产地：美国(厂家直采)

公司：

产品分类：抗生物素

公司分类： Anti_Biotin

联系Q Q： 3392242852

电话号码： 4000-520-616

电子邮箱： info@ebiomall.com

商品介绍

Format :	Purified
Amount :	100 µg
Isotype :	Mouse IgG1 Kappa
Purification :	Protein G Chromatography
Content :	25 µg in 50 µl/100 µg in 200 µl PBS containing 0.05% BSA and 0.05% sodium azide. Sodium azide is highly toxic.
Storage condition :	Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.


Gene :	AKT1
Gene ID :	207
Uniprot ID :	P31749
Alternative Name :	RAC-alpha serine/threonine-protein kinase, Protein kinase B, Proto-oncogene c-Akt
Immunogen Information :	A partial length recombinant AKT1 protein (amino acids 220-480) was used as the immunogen for this antibody

Western blot analysis: 2-4 µg/ml, Flowcytometric analysis: 0.5-1µg/10^6 cells

For Research Use Only. Not for use in diagnostic/therapeutics procedures.

Subcellular location:	Cytoplasm, Nucleus, Cell membrane
Post transnational modification:	Acetylated on Lys-14 and Lys-20 by the histone acetyltransferases EP300 and KAT2B. Acetylation results in reduced phosphorylation and inhibition of activity. Deacetylated at Lys-14 and Lys-20 by SIRT1. SIRT1-mediated deacetylation relieves the inhibition.
Tissue Specificity:	Expressed in prostate cancer and levels increase from the normal to the malignant state (at protein level). Expressed in all human cell types so far analyzed. The Tyr-176 phosphorylated form shows a significant increase in expression in breast cancers during the progressive stages i.e. normal to hyperplasia (ADH), ductal carcinoma in situ (DCIS), invasive ductal carcinoma (IDC) and lymph node metastatic (LNMM) stages.
BioGrid:	106710.302 interactions.

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