抗半胱天冬酶-14单克隆抗体（克隆：ABM1B24）/25µg/10-1009-免疫在线蚂蚁淘旗下平台

商品详细抗半胱天冬酶-14单克隆抗体（克隆：ABM1B24）/25µg/10-1009

抗半胱天冬酶-14单克隆抗体（克隆：ABM1B24）/25µg/10-1009

商品编号： 10-1009

品牌： Abeomics

市场价： ¥1800.00

美元价： 900.00

产地：美国(厂家直采)

公司：

产品分类：抗猪

公司分类： Anti_Swine

联系Q Q： 3392242852

电话号码： 4000-520-616

电子邮箱： info@ebiomall.com

商品介绍

Format :	Purified
Amount :	100 µg
Isotype :	Mouse IgG1 Kappa
Purification :	Protein G Chromatography
Content :	100 µg in 200 µl PBS containing 0.05% BSA and 0.05% sodium azide. Sodium azide is highly toxic.
Storage condition :	Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles


Gene :	CASP14
Gene ID :	23581
Uniprot ID :	P31944
Alternative Name :	CASP-14
Immunogen Information :	Full length recombinant protein of Caspase 14 was used as the immunogen for this antibody.

FACS-0.5-1µg/ml

For Research Use Only. Not for use in diagnostic/therapeutics procedures.

Subcellular location:	Cytoplasm, Nucleus
Post transnational modification:	Maturation by proteolytic processing appears to be a two-step process. The precursor is processed by KLK7 to yield the p20/p8 intermediate form which acts on the precursor to yield the p17/p10 mature form (PubMed:22825846). Initially, cleavage between Ile-152 and Lys-153 has been proposed to yield the large and small subunits of the active enzyme (PubMed:12200134).
Tissue Specificity:	Expressed in keratinocytes of adult skin suprabasal layers (from spinous layers to the stratum granulosum and stratum corneum) (at protein level). Expressed in keratinocytes of hair shaft and sebaceous glands (at protein level). In psoriatic skin only expressed at very low levels (PubMed:11175259). The p17/10 mature form is expressed in epidermis stratum corneum, the p20/p8 intermediate form in epidermis upper granular cells of the stratum granulosum (PubMed:22825846).
BioGrid:	117116.33 interactions.

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